If you're so dedicated to your business or career that your willing to change your gender in order for it to succeed you're probably a better bet than most. I'm going to go out on a limb though and predict that the number of people who would change their gender to advance their career is incredibly small. It's sort of like this story. I sincerely doubt this person is changing their gender so they can win a couple Texas high school wrestling championships. It worked out that way, but they probably would have changed their gender regardless. For every advantage you might gain by changing your gender, there's probably 100 disadvantages. It wouldn't be a smart investment in yourself if you really didn't want that change for personal reasons.