Researchers at UVa may have found a key to Alzheimer's

As an outsider wrt grant funded research at the university level I wonder (1) how much of these cuts in federal grants are warranted to eliminate expenditures not really pertinent to the performance of the actual research and (2) to what extent will the research process be improved by forcing non-profit entities to analyze and interrogate how the grant $$s are being spent?

I suspect the federal government has been overly aggressive in its “cuts” and I bet the adverse consequences of the cuts as being reported by the impacted entities are overstated. I would not take a statement by a university impacted by funding cuts to be completely honest and objective. They are now political beasts and want those taxpayer $$s back in their coffers.

 

Computer science

 

Very cool.
I am a bit surprised @mdgator05 hasn’t corrected you yet.
Let’s give it some time…

 

Again, that is incorrect.

 

Foundations, Charities, and Other Private make up about 4% of research funding, Government: 38%, private for-profit: 59%.



The Evolution of Medical Research in Texas: A Historical Overview

 

Thats strange as most have some kind of insurance and these centers charge insurance and bill co payments and deductibles. At least I know Shands does as I have paid them a lot of money out of pocket. While I can see research being cut they should still be able to see and treat patients without using research money to do it.

 

very little if any

While almost anything can be improved, I do not recall thinking that the research process was in need of improvement anytime we wrote grant applications or provided progress updates to our funding body be it the military directly, DARPA or NASA.

That said, I am a few decades on now from doing those things, but I am guessing it is not that much different now.

 

You’re guessing things haven’t changed in the past couple of decades? Ok.

 

Hopefully I can catch that wasteful reallocation of funds from those benefiting from Alzheimer's research to the rich right after church where where everyone prays for the needy, impoverished and ill...you know those who Jesus asked us to love and help. Not sure Jesus had an autopen 2000 years ago...but I do know who he hung out with according to the good book. For some reason I doubt he would be sitting court side enjoying that parade knowing who we hurt throwing it.

 

Suddenly the MAGAts who mock science are believers in the scientific research to cure Alzheimer’s. I wanna see what that contingent does if the cure to Alzheimer’s disease involves taking a vaccine lol

 

This comes immediately to mind:

Several vaccines associated with reduced risk of Alzheimer’s disease in adults 65 and older
Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer’s disease, according to new research from UTHealth Houston.

A pre-press version of a study was published online recently in the Journal of Alzheimer’s Disease. It was led by co-first authors Kristofer Harris, program manager in the Department of Neurology with McGovern Medical School at UTHealth Houston; Yaobin Ling, graduate research assistant with McWilliams School of Biomedical Informatics at UTHealth Houston; and Avram Bukhbinder, MD, an alumnus of the medical school. Paul E. Schulz, MD, the Rick McCord Professor in Neurology with McGovern Medical School, was senior author of the paper, which will appear in print in the Sept. 12 issue of the journal, Volume (95) Issue (2).

The recombinant shingles vaccine is associated with lower risk of dementia | Nature Medicine

Vaccination Reduces Risk of Alzheimer’s Disease, Parkinson’s Disease, and Other Neurodegenerative Disorders - PMC

 

This seems consistent with the OP article that implicates inflammation caused by immune responses are a factor. To the extent diseases are prevented that reduces the need for immune responses.

However it does seem like some vaccines have more impact than others.