Researchers at UVa may have found a key to Alzheimer's

.....and research funding just got cut.

 

All research?

 

You're using the wrong sources. They've been cutting chronic disease research on dementia, heart disease, ALS and Parkinson's as well. They are cruel people

A number of major Alzheimer's Disease Research Centers, some of which have operated for decades, have waited months for the Trump administration to decide whether to award them fresh five-year grants. The funding gaps have set back ongoing studies and curtailed efforts to take images of patients' brains, though the N.I.H. has recently told some centers that they would soon receive funding.

“These centers have become a safety valve for people who can’t get a neurology appointment at a private center,” said Dr. Ann Cohen, a co-director of the University of Pittsburgh Alzheimer’s center. Now, she said, things have changed. “There are fewer clinic appointments, fewer opportunities for these individuals to get brain imaging.”

The Gutting of America’s Medical Research: Here Is Every Canceled or Delayed N.I.H. Grant

 

I guess I have to explain. On the one hand, you support efforts by this administration to attack higher education including cutting funding for research such as this. On the other, you're celebrating the fruits of that university-led research. Maybe this specific funding won't be affected but the broader attacks on the higher education community will lead to fewer positive outcomes like this.

 

Yeah - republicans celebrating the dismantling of higher education and government funded research don’t get to celebrate its benefits without apologizing to all of us first.

 

They did the same thing with Build Back Better. Railed against it, voted no on it then were the first ones to be at ribbon cutting ceremonies

 

That idiot interviewer interrupted that doctor when he was giving very important information. These clowns aren't even paying attention to these researchers when they give interviews (at the 14:26 mark). Fortunately for me, I know something about the dangers of Amyloid and Tau plaque build up.

Thank you for this link. Bill, it was very informative and reinforced what I have been researching, and I learned some impotent details that I hadn't read about.

 

For anyone interested in reading versus the video

“A new way of thinking about Alzheimer’s disease has led to a discovery with the potential to stop the cognitive decline seen in patients with Alzheimer’s and other neurodegenerative diseases, according to University of Virginia researchers.

The scientists are investigating whether Alzheimer’s may result in part from the immune system’s faulty attempt to repair DNA damage in the brain.


Researchers at the UVA School of Medicine found blocking a brain-defense molecule in mice prevented memory loss and other signs of mental decline. The molecule, called STING, triggers the buildup of the toxic plaques and tangles linked to the disease.

When researchers blocked STING, the mice were protected from memory loss and other signs of mental decline.
Our findings demonstrate that the DNA damage that naturally accumulates during aging triggers STING-mediated brain inflammation and neuronal damage in Alzheimer’s disease,” said researcher John Lukens, director of UVA’s Harrison Family Translational Research Center in Alzheimer’s and Neurodegenerative Diseases. “These results help to explain why aging is associated with increased Alzheimer’s risk and uncover a novel pathway to target in the treatment of neurodegenerative diseases.”

STING, a key part of the brain’s immune system, may also contribute to Parkinson’s, ALS, dementia and other memory-related diseases. Targeting STING could lead to treatments benefiting patients with these serious conditions.”


UVA Study: Brain’s Defense System May Drive Alzheimer’s

 

Well yeah. Got to get that photo opp in order to fleece their constituents

 

What does “fresh five year grant” mean?

 

As a business owner too you always should see where the money goes and make sure it's spent wisely....that way after you find $40 of waste you can throw a wasteful $100 million parade for no one wants except you. When it's over you can just hand out millions of dollars to your wealthy friends who showed up for the parade not worrying one bit because you saved $40 early on.

 

What does "funding gap" mean?

 

Oh, and, heads around here are going to explode when they find out that one of the primary researchers who has done the imaging/brain mapping is Dr. LuLu Jiang, a former Chinese national whose undergraduate work was completed at Shandong University. Layer on the fact that much of this research is paying paid for by a 5 year grant provided by the National Institute of Health.

 

Pocket change compared to the trillions that "Autopen" spent... on nothingness. And you can speak for yourself, I want to see that parade in all it's glory.

Now... back to the interesting and possible Alzheimer breakthrough.

 

It's a crippling disease that's having a profound effect on so many lives. Sucking the joy from those with it, putting great stress on those who take care of them.
Hoping for anything that helps.

 

Anything new (so follow ups on studies like this), yes. Talk to any school involved in NIH research. New grants have dried up (and the administration is also trying to put ridiculous restrictions on them that stop them for paying to use equipment at the hospitals where they work and on who they can hire in the completion of this research).

So I hope you are happy with these results and with exactly what we know right now: the pipeline will be going very dry in the upcoming years.

 

I think if someone legit audited research dollars, where they go, and how they’re spent, they’d find a lot of waste and duplication.
My 2 cents