That's what I told a lady today, well, in so many words. Context; business luncheon today. Topic: corporate wellness. Format: panel of health and fitness professionals. When the subject turned to metabolic ward studies, the lady loudly remarked, with a chuckle, how such a study would merely reveal that her metabolism 'doesn't work.' So, boldly, I approached her afterwards, handed her my card and gently suggested that her metabolism was working just fine. She immediately became defensive and informed me that, oh no, there was something wrong with her metabolism, that she wasn't joking. Curious, I asked her if she had been diagnosed with a defective metabolism. She then altered course a bit and informed me that she'd been diagnosed pre-menopausal at the age of 36. She then clearly projected a desire to be rid of me. So, as she literally moved to almost run from me I told her, "Look, never mind me helping you. Consider that off the table for now. But can you help me ? Please, if you have the time, please email me and explain to me why working with you would be any different than working with any other female who wanted to lose weight." I'll be interested to see if she takes up the challenge. I very much fear that she's like so many for whom the diagnoses that they've gotten are now serving as a built-in excuse or even a magic talisman. But back to the thread title, no, I've STILL not seen any evidence for a broken metabolism. In the field, never mind pre-menopausal women, I see insulin-dependent diabetics losing weight in the very same way that perfectly healthy people lose weight. And seriously, which is more empowering, "I'm broken" or "I'm screwing up" ? Or, as weight-loss guru Leigh Peele puts it, "You WANT to be wrong!"