Possible cure for cancer?

Discussion in 'Too Hot for Swamp Gas' started by 96Gatorcise, Mar 28, 2014.

  1. 96Gatorcise
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    96Gatorcise Well-Known Member

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  2. DaveFla
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    "Faux News!!!"

    Derp... Derp... Derp...
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  3. HallGator
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    HallGator Administrator VIP Member

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  4. gatordowneast
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    gatordowneast Well-Known Member

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    Would this not be wonderful. Venture to say, most of us have lost a loved one to cancer.
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  5. ncgatr1
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    ncgatr1 Premium Member

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    They don't want to find a cure for cancer, there is to much money in the treatment , research, and prolonging of life.
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  6. GuyWhiteyCorngood
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    GuyWhiteyCorngood Well-Known Member

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    In this case, Fox is reporting second hand news. It's similar to the same litmus test for understanding when a woman is going to say something intelligent. You can tell if her sentence begins with: "A man once told me..." that something good might be coming.

    For Fox, they just point to Science Magazine.
  7. vertigo0923
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    vertigo0923 night owl mod VIP Member

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    :eek:

    while i agree wholeheartedly about fox, i'm also hoping you're joking on the man/woman reference.

    all in all, i think we can all agree that finding a cure for cancer would be a wonderful thing.
  8. GuyWhiteyCorngood
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    GuyWhiteyCorngood Well-Known Member

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    It was so over the top...I was hoping it was an obvious joke. But around here, I guess it's hard to tell sometimes ;)
  9. vertigo0923
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    vertigo0923 night owl mod VIP Member

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    agreed. lol. which is why i was making sure..
    ;)
  10. bayou_gator
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    bayou_gator Active Member

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    Arsenic kills 100% of cancer cells.
  11. JerseyGator01
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    JerseyGator01 Well-Known Member

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    The administrators at various voluntary health organizations like American Cancer Society regularly act like they don't want a cure. It's pretty obvious if you look at their inefficiency relative to other charities. They are poor stewards of others' money.
  12. bayou_gator
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    bayou_gator Active Member

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    One side effect of the treatment was that healthy cells were subjected to short-term attacks by the mice’s immune system, but the effect was nothing in comparison to the damage done to the cancer cells.
    .
    Seems slightly problematic....
  13. Tasselhoff
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    Tasselhoff Well-Known Member

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    1. On this thread I beg we leave the partisan carp elsewhere. Cancer sucks. For any and all.
    2. Being a survivor I pray for a cure all the time. Chemo and radiation suck almost as bad as cancer.
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  14. Tasselhoff
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    Tasselhoff Well-Known Member

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    Thanks man. It's a long road to recovery and I will always carry some scars both physically and emotionally. But seriously...it beats being dead and I am doing great.
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  15. G8trGr8t
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    Although macrophages also attacked blood cells expressing CD47 when mice were given the antibody, the researchers found that the decrease in blood cells was short-lived; the animals turned up production of new blood cells to replace those they lost from the treatment, the team reports online today in the Proceedings of the National Academy of Sciences.
  16. icequeen
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    icequeen Well-Known Member

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    Been there, too (chemo/surgery). Agree completely with you.
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  17. bayou_gator
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    bayou_gator Active Member

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    Abstract
    Macrophages play an important role in the rejection of xenogeneic cells and therefore represent a major obstacle to generating chimeric mice with human xenografts that are useful tools for basic and preclinical medical research. The signal inhibitory regulatory protein α (SIRPα) receptor is a negative regulator of macrophage phagocytic activity and interacts in a species-specific fashion with its ligand CD47. Furthermore, SIRPα polymorphism in laboratory mouse strains significantly affects the extent of human CD47-mediated toleration of human xenotransplants. Aiming to minimize macrophage activity and thus optimize human cell engraftment in immunodeficient mice, we lentivirally transduced murine CD47 (Cd47) into human liver cells. Human HepG2 liver cells expressing Cd47 were less frequently contacted and phagocytosed by murine RAW264.7 macrophages in vitro than their Cd47-negative counterparts. For the generation of human-mouse chimeric livers in immunodeficient BALB-ΔRAG/γ(c) -uPA (urokinase-type plasminogen activator) mice, freshly thawed cryopreserved human hepatocytes were transduced with a lentiviral expression vector for Cd47 using a refined in vitro transduction protocol immediately before transplantation. In vivo, Cd47-positive human primary hepatocytes were selectively retained following engraftment in immunodeficient mice, leading to at least a doubling of liver repopulation efficiencies. Conclusion: We conclude that ectopic expression of murine Cd47 in human hepatocytes selectively favors engraftment upon transplantation into mice, a finding that should have a profound impact on the generation of robust humanized small animal models. Moreover, dominance of ectopically expressed murine Cd47 over endogenous human CD47 should also widen the spectrum of immunodeficient mouse strains suitable for humanization.

    Copyright © 2012 American Association for the Study of Liver Diseases.
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  18. Gatorrick22
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    Gatorrick22 Well-Known Member

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    Because they'd have to get a real job if this works... There is a lot of 'profit' to be made in these research centers.
  19. bayou_gator
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    bayou_gator Active Member

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    This idea is at the rodent testing phase and it is far too soon for someone like faux news to be publicizing as a breakthrough is my point.
  20. Tasselhoff
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    Tasselhoff Well-Known Member

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    This idea is working at the rodent stage which is great news. It also seems your more worried about yelling about "faux" news than actually discussing what could be a breakthrough.
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